Please use this identifier to cite or link to this item: https://covid-19.conacyt.mx/jspui/handle/1000/1474
Emerging and re-emerging coronaviruses in pigs
Wang, Q
Vlasova, A
Kenney, S
Saif, L
Acceso Abierto
Atribución-NoComercial-SinDerivadas
Porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome-coronavirus (SADS-CoV) are emerging/reemerging coronaviruses (CoVs). They cause acute gastroenteritis in neonatal piglets. Sequence analyses suggest that PEDV and SADS-CoV may have originated from bat CoVs and PDCoV from a sparrow CoV, reaffirming the interspecies transmission of CoVs. The clinical signs and pathogenesis of the three viruses are similar. Necrosis of infected intestinal epithelial cells occurs, causing villous atrophy that results in malabsorptive diarrhea. The severe diarrhea and vomiting may lead to dehydration and death of piglets. Natural infection induces protective immunity, but there is no cross-protection among the three viruses. Besides strict biosecurity measures, individual vaccines are needed for each virus for disease prevention and control.
Current Opinion in Virology
2019
Preimpreso
https://coronavirus.1science.com/item/00923ad03990d81cac9c657dc7a43b2946e918ba
Inglés
VIRUS RESPIRATORIOS
Appears in Collections:Artículos científicos

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