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Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches
Lim, X
Lee, C
Pascoe, S
How, C
Chan, S
Tan, J
Yang, X
Zhou, P
Shi, Z
Sessions, O
Wang, L
Ng, L
Anderson, D
Yap, G
Acceso Abierto
Atribución-NoComercial-SinDerivadas
Bats are important reservoirs and vectors in the transmission of emerging infectious diseases. Many highly pathogenic viruses such as SARS-CoV and rabies-related lyssaviruses have crossed species barriers to infect humans and other animals. In this study we monitored the major roost sites of bats in Singapore, and performed surveillance for zoonotic pathogens in these bats. Screening of guano samples collected during the survey uncovered a bat coronavirus (Betacoronavirus) in Cynopterus brachyotis, commonly known as the lesser dog-faced fruit bat. Using a capture-enrichment sequencing platform, the full-length genome of the bat CoV was sequenced and found to be closely related to the bat coronavirus HKU9 species found in Leschenault's rousette discovered in the Guangdong and Yunnan provinces.
The Journal of General Virology
2019
Preimpreso
https://coronavirus.1science.com/item/68e7636774c2143987383f3f1df1c53189235b39
Inglés
VIRUS RESPIRATORIOS
Aparece en las colecciones: Artículos científicos

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