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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/1392| Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: A retrospective study | |
| Alqahtani, F Aleanizy, F Ali El Hadi Mohamed, R Alanazi, M Mohamed, N Alrasheed, M Abanmy, N Alhawassi, T | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening respiratory disease with a high case fatality rate; however, its risk factors remain unclear. We aimed to explore the influence of demographic factors, clinical manifestations and underlying comorbidities on mortality in MERS-CoV patients. Retrospective chart reviews were performed to identify all laboratory-confirmed cases of MERS-COV infection in Saudi Arabia that were reported to the Ministry of Health of Saudi Arabia between 23 April 2014 and 7 June 2016. Statistical analyses were conducted to assess the effect of sex, age, clinical presentation and comorbidities on mortality from MERS-CoV. A total of 281 confirmed MERS-CoV cases were identified: 167 (59.4%) patients were male and 55 (20%) died. Mortality predominantly occurred among Saudi nationals and older patients and was significantly associated with respiratory failure and shortness of breath. Of the 281 confirmed cases, 160 (56.9%) involved comorbidities, wherein diabetes mellitus, hypertension, ischemic heart disease, congestive heart failure, end-stage renal disease and chronic kidney disease were significantly associated with mortality from MERS-CoV and two or three comorbidities significantly affected the fatality rates from MERS-CoV. The findings of this study show that old age and the existence of underlying comorbidities significantly increase mortality from MERS-CoV. | |
| Epidemiology and Infection | |
| 2019 | |
| Preimpreso | |
| https://coronavirus.1science.com/item/be3f1831042b8018d8176941a35fd6e71d8b9c32 | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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