Please use this identifier to cite or link to this item: https://covid-19.conacyt.mx/jspui/handle/1000/1386
Coronavirus infections and immune responses
Li, G
Fan, Y
Lai, Y
Han, T
Li, Z
Zhou, P
Pan, P
Wang, W
Hu, D
Liu, X
Zhang, Q
Wu, J
Acceso Abierto
Atribución-NoComercial-SinDerivadas
Coronaviruses (CoVs) are by far the largest group of known positive-sense RNA viruses having an extensive range of natural hosts. In the past few decades, newly evolved Coronaviruses have posed a global threat to public health. The immune response is essential to control and eliminate CoV infections, however, maladjusted immune responses may result in immunopathology and impaired pulmonary gas exchange. Gaining a deeper understanding of the interaction between Coronaviruses and the innate immune systems of the hosts may shed light on the development and persistence of inflammation in the lungs and hopefully can reduce the risk of lung inflammation caused by CoVs. In this review, we provide an update on CoV infections and relevant diseases, particularly the host defense against CoV-induced inflammation of lung tissue, as well as the role of the innate immune system in the pathogenesis and clinical treatment.
Journal of Medical Virology
2020
Preimpreso
https://coronavirus.1science.com/item/9831bf9ead6e9854effbbceec1569c2ba77c9d54
Inglés
VIRUS RESPIRATORIOS
Appears in Collections:Artículos científicos

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