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http://conacyt.repositorioinstitucional.mx/jspui/handle/1000/104| Patterns of the COVID19 epidemic spread around the world: exponential vs power laws | |
| Natalia L. Komarova Dominik Wodarz | |
| Acceso Abierto | |
| Atribución-NoComercial-SinDerivadas | |
| 10.1101/2020.03.30.20047274 | |
| We have analyzed the COVID19 epidemic data of more than 174 countries (excluding China) in the period between January 22 and March 28, 2020. We found that some countries (such as the US, the UK, and Canada) follow an exponential epidemic growth, while others (like Italy and several other European countries) show a power law like growth. At the same time, regardless of the best fitting law, most countries can be shown to follow a trajectory similar to that of Italy, but with varying degrees of delay. We found that countries with ``younger" epidemics tend to exhibit more exponential like behavior, while countries that are closer behind Italy tend to follow a power law growth. We hypothesize that there is a universal growth pattern of this infection that starts off as exponential and subsequently becomes more power law like. Although it cannot be excluded that this growth pattern is a consequence of social distancing measures, an alternative explanation is that it is an intrinsic epidemic growth law, dictated by a spatially distributed community structure, where the growth in individual highly mixed communities is exponential but the longer term, local geographical spread (in the absence of global mixing) results in a power-law. This is supported by computer simulations of a metapopulation model that gives rise to predictions about the growth dynamics that are consistent with correlations found in the epidemiological data. Therefore, seeing a deviation from straight exponential growth may not be a consequence of working non-pharmaceutical interventions (except for, perhaps, restricting the air travel). Instead, this is a normal course of raging infection spread. On the practical side, this cautions us against overly optimistic interpretations of the countries epidemic development and emphasizes the need to continue improving the compliance with social distancing behavior recommendations. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement Support of grant NSF DMS 1662146/1662096 (NK & DW) is gratefully acknowledged. The authors or their institution never received payment or services from a third party for any aspect of the submitted work ### Author Declarations All relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript. Yes All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes All data that are analyzed in this paper have been obtained from an online repository. The data are freely available for download at this site, and the web location is specified in the paper. <https://datahub.io/core/covid-19#data-cli> | |
| Cold Spring Harbor Laboratory Press | |
| 2020 | |
| Preimpreso | |
| https://www.medrxiv.org/content/10.1101/2020.03.30.20047274v1 | |
| Inglés | |
| VIRUS RESPIRATORIOS | |
| Aparece en las colecciones: | Artículos científicos |
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| 200472741.pdf | 10.25 MB | Adobe PDF | Visualizar/Abrir |